The stock market is buzzing with pre-market activity today, with several companies experiencing significant price changes. Leading the charge is Exicure, Inc. (XCUR), whose shares soared 49.3% to $2.39 after the company successfully entered into debt-for-equity exchange agreements and regained compliance with Nasdaq listing standards. This positive news seems to have fueled investor confidence in the company.
Another notable gainer is NuCana plc (NCNA), which saw its shares jump 94.4% to $4.94. This surge follows the presentation of final data from the Phase 2 Nutide:701 study at the ESMO Congress. The data showcased the efficacy of NUC-7738 in combination with pembrolizumab for patients with metastatic melanoma who had previously failed or relapsed on PD-1 inhibitor therapy. This promising news has clearly piqued investor interest in NuCana’s potential.
On the other side of the spectrum, Rafael Holdings, Inc. (RFL) experienced a significant decline, with shares falling 40.1% to $1.00. This sharp drop comes after a 9% gain on Friday, indicating a potential shift in market sentiment towards the company. While no specific news has been announced to explain this drop, investors may be reacting to factors beyond the immediate public information.
Beyond these prominent movers, several other companies are making waves in pre-market trading. Dermata Therapeutics, Inc. (DRMA) rose 73.4% after a 7% gain on Tuesday, while Agape ATP Corporation (ATPC) gained 53.1% following a strategic collaboration announcement. Tenon Medical, Inc. (TNON) also saw a 22.1% rise after announcing a $4.5 million public offering.
In the technology sector, iTeos Therapeutics, Inc. (ITOS) climbed 20.1% after releasing positive data from a Phase 2 study. IO Biotech, Inc. (IOBT) followed suit, gaining 18.2% after presenting data from a Phase 2 trial. Yunji Inc. (YJ) and Adagene Inc. (ADAG) also saw significant gains, rising 14.3% and 13.7% respectively.
Among the losers, Presidio Property Trust, Inc. (SQFT) fell 20.4%, Psyence Biomedical Ltd. (PBM) dropped 16.7% after receiving a delisting determination from Nasdaq, and Edgio, Inc. (EGIO) declined 14.7%.
As the trading day progresses, it will be interesting to see how these pre-market movers perform and what factors ultimately drive their share prices.
