Recent research has revealed the mechanism behind aspirin’s protective effect against bowel cancer. Aspirin, a common painkiller, has been shown to boost the body’s immune response to cancer cells.
When aspirin is ingested, it is absorbed into the colon, where it interacts with immune cells. The researchers discovered that aspirin increases the expression of a protein called CD80 on certain immune cells. This enhanced CD80 expression allows the immune cells to more effectively alert other immune cells to the presence of tumor-associated proteins. As a result, the immune system becomes more efficient at recognizing and destroying cancer cells.
The study supports previous findings that aspirin use can reduce the risk of developing bowel cancer. Additionally, it suggests that aspirin may be particularly effective in preventing rectal cancer. Rectal cancer patients who took aspirin had higher CD80 expression in healthy rectal tissue, indicating that aspirin can boost the immune system’s surveillance abilities within the colon.
While aspirin has been shown to have beneficial effects against bowel cancer, it’s important to note that it should only be taken under the guidance of a healthcare professional. Long-term aspirin use can have potential side effects, so it’s crucial to consult with a doctor before starting an aspirin regimen for cancer prevention.