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KKR, a global investment firm, has acquired Immedica Pharma, a Stockholm-based pharmaceutical company specializing in rare diseases and specialty care products. The acquisition will involve the reinvestment of Immedica’s existing owner, Impilo, which will become an equal owner alongside KKR. The partnership aims to support Immedica’s continued growth, including the launch of its recently approved ultra-orphan drug Loargys, additional pipeline assets, and continued in-licensing and mergers and acquisitions.

Researchers have developed a new technology called tARC-seq that enables the accurate detection of rare SARS-CoV-2 mutations. Using tARC-seq, they found that the virus’s mutation rate is higher than initially expected and identified hotspots for mutations. Their findings also revealed template switching and complex mutations as mechanisms driving SARS-CoV-2’s rapid evolution. This technology can be used to monitor viral evolution and aid in the development of effective vaccines.

Researchers have developed a non-invasive method to detect drug use by analyzing fingerprints and surface traces on smartphones. This method could provide a more convenient and anonymous way to collect data on drug use patterns, which could help inform treatment decisions and public health initiatives.

The European Centre for Disease Prevention and Control (ECDC) has issued a warning about the increase in measles and pertussis cases across the European Union. Measles cases have risen significantly since 2023, with over 5,700 cases reported between March 2023 and February 2024, resulting in five deaths. Pertussis cases have also increased tenfold compared to the previous two years. These diseases, while vaccine-preventable, continue to circulate and pose a threat to the unvaccinated or vulnerable populations. To curb transmission, the ECDC emphasizes the importance of vaccination, highlighting its protective effects not only for individuals but also for those unable to receive vaccines due to age or compromised immune systems.

A study published in The Obesity Journal shows that thousands of people referred to the NHS Digital Weight Management Programme lost an average of half a stone in 12 weeks. The program involves diet and exercise advice and is available to adults in England with a BMI over 30 and either diabetes or high blood pressure, or with BMIs of 27.5 or more if they are from Black, Asian or minority ethnicities. Of those who started the scheme, the average weight lost was 4.85lb (2.2kg). The NHS tips for healthy weight loss include reading about healthy eating and exercise, setting realistic goals, and making gradual changes to your lifestyle.

A recent study suggests that the strength of the therapist-participant relationship is a more significant factor in reducing depression through psychedelic-assisted therapy than the drug effects themselves. The study analyzed data from a clinical trial that found psilocybin (magic mushrooms) combined with psychotherapy was effective in treating major depressive disorder. The results showed that the stronger the therapeutic alliance, the lower the depression scores were one year later, indicating the importance of a strong relationship in psychedelic-assisted therapy.

A recent study has highlighted the significant role community pharmacies play in assisting individuals seeking to quit smoking. The study’s findings, published in the journal Pharmacy, emphasize the importance of implementing tobacco cessation services within pharmacies and identifying potential barriers to their full effectiveness.

Hong Kong has implemented a ban on single-use plastics, sparking mixed reactions among residents. Chief Executive John Lee Ka-chiu has expressed concerns over the supply and affordability of replacement products, emphasizing the need for a collective effort towards environmentalism. While some businesses have opted to offer alternatives, others like the LH Group have temporarily closed takeaway services to avoid hassle. Lee remains optimistic about the policy’s long-term impact and encourages the use of reusable cutlery as an alternative solution.

Antipsychotic use in people with dementia is associated with increased risks of various serious health outcomes, including stroke, blood clots, heart attack, pneumonia, and acute kidney injury. These risks are particularly high in the early stages of treatment. Antipsychotics are commonly prescribed for behavioral and psychological symptoms of dementia, but their use should be carefully considered due to the potential for adverse effects. Further research is needed to explore safer alternatives for managing these symptoms.

Researchers have identified key barriers to vaccine uptake for whooping cough, flu, and Covid-19 in pregnant women. These barriers include concerns about safety, lack of knowledge, fear of adverse effects, and lack of endorsement from healthcare professionals. To address these barriers, researchers recommend focusing on “five Cs” – confidence, complacency, convenience, communication, and context. By implementing these recommendations in public health strategies, we can increase protection of mothers-to-be and their children.