MIRA Pharmaceuticals’ Ketamir-2 Shows Promise in Reversing Neuropathic Pain

MIRA Pharmaceuticals’ Ketamir-2 Shows Promise in Reversing Neuropathic Pain

MIRA Pharmaceuticals’ oral ketamine analog, Ketamir-2, has demonstrated significant potential in reversing neuropathic pain in a recent preclinical study. The drug showed superior efficacy compared to traditional oral ketamine, achieving complete normalization of pain thresholds in rats. MIRA is optimistic about the potential of Ketamir-2 for treating neuropathic pain and cancer-induced depression, with human trials potentially starting as early as 2025.

UK’s NHS Likely to Block Eli Lilly’s Donanemab for Alzheimer’s, Following Leqembi Rejection

UK’s NHS Likely to Block Eli Lilly’s Donanemab for Alzheimer’s, Following Leqembi Rejection

The UK’s National Health Service (NHS) is expected to follow the National Institute for Health and Care Excellence (NICE) in rejecting Eli Lilly’s donanemab, a potential Alzheimer’s treatment, due to safety concerns, high costs, and a precedent set by the rejection of Biogen’s Leqembi. While donanemab showed promising results in slowing cognitive decline, the risks of brain bleeds and swelling, occurring at a higher rate than with Leqembi, are major concerns. The projected cost of donanemab, estimated to be 25% higher than Leqembi, adds to the concerns, with NICE already citing cost as a primary factor in its rejection of Leqembi.

Malawi Implements Mandatory Mpox Screening at Entry Points to Prevent Outbreak

Malawi Implements Mandatory Mpox Screening at Entry Points to Prevent Outbreak

Malawi has introduced mandatory Mpox screening at all entry ports following the identification of two suspected cases. The country is taking precautionary measures to prevent a potential outbreak, despite having avoided a significant Mpox spread previously. The Health Ministry is preparing for a worst-case scenario and has established a mobile diagnostic unit and launched awareness campaigns.

Scroll to Top