Nitazenes, a class of synthetic opioids, have emerged as a serious threat, with their presence now detected in the United Kingdom. A BBC investigation has uncovered accounts selling nitazenes on platforms like SoundCloud and X, highlighting the illicit trade of these substances. The investigation revealed that suppliers are using innovative methods to evade customs, including concealing the opioids within dog food and catering products. The potency of nitazenes is a major concern, as some derivatives are estimated to be 100 times stronger than heroin and 40 times stronger than fentanyl, posing a significant risk of overdose and fatalities. In the UK, over 100 deaths have been linked to nitazenes, with fatalities steadily increasing. Experts have expressed concerns about the lack of prompt action in tracking non-fatal overdoses involving nitazenes, emphasizing the importance of data collection to monitor the spread of these drugs and prevent future deaths. Understanding nitazenes is crucial for recognizing the dangers associated with their use. These substances are derivatives of benzodiazepines, a class of psychoactive drugs used to treat anxiety and insomnia. However, nitazenes have gained popularity in the recreational drug scene due to their sedative and anxiolytic effects. They are often found in various forms, including powders, pills, or liquids, and are sometimes missold as oxycodone tablets or laced with other substances. Nitazenes have distinct pharmacological properties, primarily acting on gamma-aminobutyric acid (GABA) receptors in the brain. This action leads to enhanced inhibitory neurotransmission and produces sedative, hypnotic, and anxiolytic effects. While nitazenes are less potent than fentanyl, their varying potency depending on the specific compound makes them equally dangerous. Fentanyl, a synthetic opioid used medically, is also illicitly manufactured and has been implicated in overdose deaths worldwide. Taking nitazenes poses significant risks, especially in high doses or without medical supervision. Some of the dangers associated with nitazene use include respiratory depression, coma, seizures, and death. It is important to recognize the signs of an overdose, which may include: unconsciousness, shallow breathing, blue or pale skin, pinpoint pupils, and seizures. If an overdose is suspected, it is critical to call for emergency medical assistance immediately. Naloxone, a drug that can reverse the effects of an opioid overdose, should be administered if available while waiting for medical help. The UK has several helplines that provide confidential advice, support, and information to individuals struggling with drug or alcohol dependence. These helplines are staffed by trained professionals who can offer guidance on treatment options and local support services.
Deadly Nitazenes: Synthetic Opioids Smuggled into UK in Dog Food Tins
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