BridgeBio Pharma’s Attruby (acoramidis) receives FDA approval for treating ATTR-CM, marking a significant advancement in addressing this rare cardiovascular disease. The drug’s unique mechanism and positive Phase 3 trial results offer hope for patients, while its market positioning relative to Pfizer’s tafamidis sparks industry discussion.
BridgeBio Pharma’s acoramidis demonstrated significant reductions in all-cause mortality and recurrent cardiovascular-related hospitalizations in patients with ATTR-CM, a debilitating heart condition. The positive results from the Phase 3 ATTRibute-CM study highlight the potential of acoramidis as a first-line therapy for ATTR-CM, offering hope for improved quality of life for patients.
BridgeBio Pharma presented positive data from its Phase 3 ATTRibute-CM study of acoramidis in ATTR-CM at the European Society of Cardiology (ESC) 2024, showcasing a significant increase in serum TTR levels in patients who switched to acoramidis. The FDA has accepted the company’s marketing application with a PDUFA date of November 29th, and BridgeBio has secured exclusive commercial rights for Europe with Bayer AG.
