Air travel can significantly impact our lungs due to reduced air pressure in the cabin. Most people adapt without complications, but some may experience discomfort, fatigue, or shortness of breath. Health expert Dr. Lawrence Cunningham advises staying hydrated, moving around, using saline nasal spray, and practicing deep breathing exercises to combat the effects of low oxygen levels. Individuals with respiratory conditions like COPD or asthma may need to consult their doctors before flying and consider supplemental oxygen during the flight.