Ensemble, a Moncton harm-reduction organization, has detected xylazine in 10% of tested drugs since January. Xylazine, an animal tranquilizer, can lead to fatal outcomes when mixed with opioids. Unlike opioids, naloxone cannot reverse its effects, and there is no pharmaceutical antidote. Ensemble warns of the severe risk of necrotic wounds, especially among their vulnerable population. Since 2019, Health Canada has noted an increase in xylazine detections in drug samples. In New Brunswick, the drug was first identified in 2016, with one recorded death linked to it. The province’s Public Health department advises precautions for street drug users, including using overdose prevention sites and starting with small amounts.