Throughout history, misinformation about diseases has posed a significant challenge. In the late 19th century, Canada faced a devastating smallpox epidemic, which was fueled in part by the anti-vaccination movement led by physicians like Alexander Milton Ross and Joseph Emery Coderre. They spread false claims about the dangers of vaccination and downplayed the threat of the disease. Despite scientific evidence supporting the safety and efficacy of vaccination, the anti-vaccination movement found traction among the population, particularly in the French Canadian community. Their actions contributed to a large number of deaths that could have been prevented. The parallels between the anti-vaccination movement of the past and present are striking. The spread of misinformation through social media, the distrust of scientific experts, and the promotion of unproven treatments continue to undermine public health efforts and put lives at risk.