Enveric Biosciences’ EB-003 Shows Promise: Non-Hallucinogenic Psychedelic for Depression and Anxiety Clears Preclinical Hurdles

Enveric Biosciences announces successful preclinical pharmacokinetic (PK) studies for its lead drug candidate, EB-003, a non-hallucinogenic DMT analog designed to treat depression and anxiety. The results show significant brain penetration and pave the way for an Investigational New Drug (IND) application in 2025, targeting a multi-billion dollar market.

Relaxation, Not Mystical Experiences, Key to Psychedelic Therapy Success: Study

A groundbreaking study published in the Journal of Psychopharmacology reveals that feelings of relaxation, rather than mystical experiences, are the strongest predictor of positive outcomes in psychedelic-assisted therapy for treating mental health disorders. The research, conducted at the University of Fribourg in Switzerland, challenges the prevailing belief that transformative experiences like ego dissolution drive the antidepressant effects of psychedelics.

Psychedelic Drug DOI Reduces Anxiety by Activating Specific Brain Cells, Study Finds

Researchers at Johns Hopkins University have discovered that the psychedelic drug DOI (2,5-dimethoxy-4-iodoamphetamine) reduces anxiety by activating specific neurons in the brain. The study, published in Neuron, reveals that DOI works by influencing parvalbumin-positive interneurons in the ventral hippocampus, leading to a decrease in anxiety-related activity. The findings suggest potential therapeutic benefits for anxiety disorders without the hallucinogenic effects commonly associated with psychedelics.

Stress: How It Affects Your Brain, Body, and Everyday Life

Stress is a common experience, but it can have a significant impact on our mental and physical well-being. This article explores the science behind stress, detailing how it affects the brain and body, and provides practical tips for managing stress effectively. Learn about the signs of stress, the dangers of chronic stress, and resources for seeking help.

Ariana Grande Apologizes to Elvira for ‘Rude’ Behavior Seven Years Ago

Pop star Ariana Grande has issued a public apology to horror icon Elvira, also known as Cassandra Peterson, for her perceived rudeness at a Halloween event seven years ago. Elvira revealed that Grande refused a photo request and left before the event started, leaving her family and friends behind. Grande admitted to being in a state of anxiety at the time, but offered a sincere apology for any offense caused.

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