Eli Lilly’s Donanemab Shows Promise: Modified Dosing Reduces ARIA-E Risk in Alzheimer’s Patients

Eli Lilly and Company (LLY) announced positive results from its TRAILBLAZER-ALZ 6 study, demonstrating a significant reduction in ARIA-E, a side effect associated with Alzheimer’s treatments, in patients receiving a modified dosing regimen of donanemab. The study revealed a 41% lower relative risk of ARIA-E in the modified group compared to standard dosing, with the most notable reduction seen in patients carrying the APOE4 gene, a known risk factor for Alzheimer’s.

Eli Lilly’s Donanemab Shows Promise: Modified Dosing Reduces ARIA-E Risk in Alzheimer’s Patients

Eli Lilly and Company (LLY) announced positive results from its TRAILBLAZER-ALZ 6 study, demonstrating a significant reduction in ARIA-E, a side effect associated with Alzheimer’s treatments, in patients receiving a modified dosing regimen of donanemab. The study revealed a 41% lower relative risk of ARIA-E in the modified group compared to standard dosing, with the most notable reduction seen in patients carrying the APOE4 gene, a known risk factor for Alzheimer’s.

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