Russia to Roll Out Free Personalized mRNA Cancer Vaccine in 2025

Russia is set to introduce a free, personalized mRNA cancer vaccine in early 2025. Tailored to individual patients’ tumors, the vaccine aims to stimulate an immune response against cancer cells. This development comes amid a global surge in cancer cases and underscores the increasing focus on personalized cancer therapies. The vaccine’s exact applications and name remain undisclosed, but it represents a significant step in the fight against cancer.

Goldman Sachs Upgrades BioNTech on Promising Cancer Drug BNT327

Goldman Sachs has upgraded BioNTech (BNTX) to Buy, citing the company’s BNT327, an immuno-oncology asset in clinical development. Data from Summit Therapeutics and Akeso for ivonescimab (PD-1xVEGF bispecific) has shown potential to challenge standard-of-care regimens across various solid tumors, sparking interest in BioNTech’s bispecific drug. Goldman analysts believe BNT327 has the potential to drive BioNTech toward becoming a leading player in oncology, making current stock levels an attractive entry point for investors.

Dragonfly Therapeutics Presents Promising Preclinical Data for DF6215 and DF9001 at SITC Annual Conference

Dragonfly Therapeutics, a clinical-stage biotech company, showcased preclinical data for its novel immunotherapies, DF6215 and DF9001, at the Society for Immunotherapy of Cancer (SITC) Annual Conference. DF6215, an engineered IL-2 cytokine, demonstrated superior therapeutic benefits compared to traditional IL-2 therapies, while DF9001, an EGFR-targeting TriNKET, exhibited potent anti-tumor activity through both EGFR-signal inhibition and immune-mediated mechanisms. Both candidates showed promising safety profiles, highlighting their potential for treating advanced solid tumors.

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