In a groundbreaking medical advancement, a 54-year-old grandmother named Lisa Pisano has successfully received the first-ever combined transplant of a gene-edited pig kidney and a mechanical heart pump. The innovative procedure, performed by surgeons at NYU Langone Health, offers hope to individuals facing end-stage organ failure and a shortage of human organ donations. Pisano, who suffers from both end-stage kidney disease and heart failure, was not a candidate for a traditional heart and kidney transplant due to her complex medical conditions. However, the combined pig kidney and heart pump transplant has provided her with a new lease on life.