A groundbreaking study reveals that fat cells retain a ‘memory’ of past obesity, potentially explaining why weight loss is so difficult to maintain. Epigenetic changes in fat cells, even after weight loss, may prime them for rapid regrowth when exposed to high-fat foods. This discovery sheds light on the complex interplay of factors contributing to weight cycling and highlights the importance of early intervention.
A new test utilizing cheek cells shows promising potential in predicting the risk of death within a year. This epigenetic clock, named CheekAge, analyzes patterns in DNA methylation to estimate a person’s ‘biological age,’ which may be a better indicator of health than chronological age. While it cannot predict death with certainty, the test can help individuals understand their mortality risk and potentially make lifestyle changes for better health.
A small study suggests that following a vegan diet for two months may slow aging by altering DNA methylation patterns. However, experts caution that the findings need further investigation, considering the study’s short duration and potential influence of calorie restriction.
Tech entrepreneur Bryan Johnson claims to have reversed his epigenetic age by 5.1 years through a comprehensive anti-aging regimen that costs him over $2 million annually. Project Blueprint, as it is called, involves consuming over 100 supplements and adhering to a strict diet. Johnson’s transformation is attributed to a rude awakening that led him to pursue maximizing his health through scientific advancements.
