A study published in BMJ Global Health reveals significant disparities between national COVID-19 therapeutic guidelines and recommendations from the World Health Organization (WHO). Researchers analyzed guidelines from 109 WHO member countries and found that many deviated substantially from WHO standards, particularly in low-resource areas. Ninety-three percent of national guidelines recommended unauthorized or ineffective medications, and only 10% advised corticosteroids for severe illness despite evidence of their benefits. The findings highlight the need for standardized procedures for developing national guidelines based on the best available evidence.