US stocks traded lower on Tuesday, with the Dow Jones Industrial Average falling over 1%, the Nasdaq Composite dropping 2.22%, and the S&P 500 declining 1.28%. The ISM manufacturing PMI rose to 47.2 in August but missed market expectations. Several stocks saw significant price changes, including Sify Technologies Limited and SPAR Group, Inc., which surged, while IO Biotech, Inc. and Dyne Therapeutics, Inc. experienced declines.