Fatty liver disease, an accumulation of fat in the liver, progresses to liver cirrhosis, liver failure, or liver cancer. Swelling in body parts during liver cirrhosis can signal advanced liver disease and requires immediate medical attention. Symptoms such as leg, ankle, and abdominal swelling, as well as puffiness in the face and hands, indicate severe fatty liver disease. Early diagnosis, lifestyle changes, and appropriate treatment can help manage fatty liver disease and prevent irreversible damage.