Merck & Moderna’s V940 Shows Promise in Lung Cancer Treatment: Phase 3 Trial Begins

Merck & Co. Inc. (MRK) and Moderna, Inc. (MRNA) have initiated a pivotal Phase 3 trial for their investigational neoantigen therapy, V940 (mRNA-4157), in combination with Keytruda (pembrolizumab) for non-small cell lung cancer (NSCLC) patients. This trial, known as INTerpath-009, focuses on patients who did not achieve a complete response after receiving neoadjuvant Keytruda plus chemotherapy. The first patients have started enrolling in Canada, and global recruitment is ongoing. This development follows a series of other trials evaluating V940 in combination with Keytruda for different types of cancers.

Cathie Wood’s Ark Invest Makes Major Moves: Block, Moderna, and Robinhood Shares Sold

Cathie Wood’s Ark Invest has been active in the market this week, making significant trades involving Block Inc (SQ), Moderna Inc (MRNA), and Robinhood Markets Inc (HOOD). The fund sold off shares of Block, despite the company’s recent positive second-quarter earnings. Ark also sold off shares of Moderna, following the company’s announcement of its post-Covid roadmap. Additionally, the fund divested from Robinhood, despite the platform’s expansion into futures and index options trading. Ark Invest also made purchases in several other companies, including Intellia Therapeutics, CRISPR Therapeutics, and Tempus AI.

GSK Sues Moderna Over mRNA Vaccine Patent Infringement: A Battle for Vaccine Technology Supremacy

Pharmaceutical giant GSK has filed a lawsuit against Moderna, claiming that Moderna’s mRNA vaccines infringe on patents developed by GSK. GSK asserts that its groundbreaking mRNA vaccine platform, pioneered over a decade ago, is the foundation for Moderna’s successful vaccines. This lawsuit highlights a major battle over intellectual property rights in the rapidly developing field of mRNA vaccines, with implications for future vaccine development and the global fight against infectious diseases.

Alnylam Drops Patent Infringement Case Against Moderna

Alnylam Pharmaceuticals has dropped its patent infringement lawsuit against Moderna, conceding that Moderna’s COVID-19 vaccine formulation does not infringe on its patents. The case centered around Alnylam’s patent on lipid nanoparticle (LNP) technology used for delivering genetic material into cells. The settlement allows for the entry of judgment in favor of Moderna, effectively ending the legal dispute.

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