BofA Securities has upgraded Fulcrum Therapeutics (FULC) ahead of the company’s Phase 3 readout for losmapimod, a potential treatment for Facioscapulohumeral muscular dystrophy (FSHD). The analyst cites optimism from key opinion leaders about the upcoming results, based on the functional benefits seen in Phase 2 using the ‘reachable workspace’ (RWS) endpoint. While the analyst acknowledges uncertainties about the study’s success, they have increased the likelihood of success from 35% to 50%.
Following the successful conclusion of the second phase on April 26, Phase 3 of the 2024 Lok Sabha Elections is set to take place on May 7. The upcoming phase will involve 89 constituencies across various regions of the country, including 11 constituencies in Maharashtra. As part of the safety measures, schools and colleges in these constituencies will remain closed on election day. This decision aims to ensure the safety of students and staff while minimizing disruptions during the voting process. By closing educational institutions, it also facilitates smoother movement for election officials and voters, encouraging wider participation in the election.
