Individuals who utilize acid-reducing medications, such as proton pump inhibitors and H2 blockers, may exhibit an elevated risk of experiencing migraines and severe headaches, as per a study published in Neurology ® Clinical Practice. The study, which involved over 11,000 participants, revealed that individuals taking proton pump inhibitors were 70% more likely to experience migraines, while those using H2 blockers were 40% more likely, and antacid supplement users were 30% more likely. While the study does not establish a causal relationship, it does suggest an association between acid-reducing drugs and migraine occurrence. Given the widespread use of these medications, further research is warranted to explore this potential link.