Could Rubbing Neosporin in Your Nose Prevent Colds and the Flu?

A new study suggests that applying Neosporin ointment to the inside of the nose may help protect against respiratory viruses like those that cause COVID-19 and the flu. The study found that Neosporin triggers an immune response that creates a barrier against viruses. However, more research is needed to confirm whether this approach is effective in preventing infections in humans.

Intranasal Neomycin Elicits Broad-Spectrum Antiviral Immunity in the Upper Respiratory Tract

Respiratory viruses, such as influenza and SARS-CoV-2, pose a significant threat to global health. Despite advancements in vaccines and therapies, these viruses remain a major public health concern. A recent study investigated the potential of intranasal neomycin administration to induce antiviral protection in murine models. The findings revealed that intranasal neomycin evoked robust expression of interferon-stimulated genes (ISGs) in the upper respiratory tract, providing protection against both influenza A virus and SARS-CoV-2. This protection was independent of the host microbiome or interferon-related pathways. The study highlights the therapeutic and prophylactic potential of neomycin against respiratory viruses.

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