RNA Isoforms Linked to Alzheimer’s Disease, Study Finds

Different versions of RNA encoded by single genes may play a role in Alzheimer’s disease, according to a new study published in the journal ‘Science Advances’. The researchers analyzed brain tissue from deceased organ donors and found 700 RNA isoforms that had never been described before. Notably, the genes behind these isoforms were equally active in both groups of people with and without Alzheimer’s. However, the levels of nearly 100 of these isoforms differed in the brains of people with and without Alzheimer’s.

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