Vitamin B12 Deficiency: Symptoms, Causes, and What You Need to Know

Do you find yourself constantly tired, struggling to catch your breath, or having trouble focusing? These symptoms could be linked to a vitamin B12 deficiency. Vitamin B12 is a vital nutrient, one of the B vitamins, essential for proper bodily functions, alongside vitamins D, A, and C. Also known as cobalamin, vitamin B12 plays a crucial role in several key processes: amino acid metabolism, cell renewal, and the synthesis of DNA and RNA. It contributes to the production of red blood cells and bone marrow, helps lower cholesterol levels, and ensures proper nerve function. Moreover, vitamin B12 helps convert nutrients into energy, allowing us to lead active lifestyles. Vitamin B12 also participates in the production of dopamine and norepinephrine, hormones released in response to stress. By supporting the synthesis of these hormones, vitamin B12 can help reduce stress and fatigue, boost energy levels, improve concentration, and enhance cognitive function.

Our bodies do not naturally produce vitamin B12, making it essential to ensure adequate intake through a balanced diet or supplements. A low vitamin B12 level is diagnosed when blood tests show levels below the ideal range of 200 to 950 picograms per millilitre (pg/ml). Levels below 200 pg/ml indicate a deficiency, while levels above 950 pg/ml suggest an excess.

Vitamin B12 deficiency arises when the body doesn’t receive sufficient intake, struggles to absorb it properly, or faces difficulties storing it. One manifestation of vitamin B12 deficiency is pernicious anaemia, a specific type of anaemia that develops gradually. This slow progression allows the body to adapt, which can be dangerous as it masks more serious underlying issues that might not be immediately apparent through symptoms. The bodily symptoms of vitamin B12 deficiency include:

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Fatigue and weakness:

One of the most common symptoms, as vitamin B12 is essential for energy production.
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Shortness of breath:

A result of reduced red blood cell production, leading to impaired oxygen transport.
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Pale skin:

Due to the low red blood cell count, which gives the skin a pale appearance.
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Headache and dizziness:

Caused by a lack of oxygen and nutrients reaching the brain.
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Numbness and tingling:

A common symptom affecting the hands, feet, or face, due to nerve damage.
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Constipation:

Caused by slowed digestion due to impaired nerve function.
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Loss of appetite and weight loss:

A result of reduced energy levels and difficulty absorbing nutrients.
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Mental fog and concentration problems:

Vitamin B12 is crucial for brain function and cognitive abilities.
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Depression and mood swings:

Linked to the impact of vitamin B12 deficiency on brain chemistry.
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Irritability and anxiety:

Also linked to the deficiency’s effect on brain chemistry and neurotransmitter production.
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Pins and needles sensation:

A symptom of nerve damage caused by vitamin B12 deficiency.
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Vision problems:

A result of impaired nerve function affecting the eyes.

Vitamin B12 deficiency is often observed in individuals experiencing intense and chronic headaches. A study published in the official journal of the Brazilian Academy of Neurology, Arquivos de Neuro-Psiquiatria, highlighted this correlation. The study noted that a lack of vitamin B12, coupled with excess homocysteine in the blood, can damage the cells lining blood vessels. This damage increases free radical levels, potentially contributing to the onset of migraine episodes. Research suggests that people with chronic migraines and frequent, intense headaches tend to have lower vitamin B12 levels compared to those with less frequent and less severe episodes. This deficiency might be exacerbated by increased use of analgesics (pain-relieving medication), which can hinder vitamin B12 absorption.

Vitamin B12 is essential for athletes due to its crucial role in producing red blood cells, responsible for oxygen transport to muscles. As athletes push their bodies harder, their muscles require more oxygen to perform optimally. Vitamin B12 also aids in converting food into glucose, the body’s primary energy source, crucial for athletes to maintain energy levels during workouts. Additionally, it supports the proper functioning of the nervous system, helping prevent neurological damage that can arise from intense physical activity.

Given vitamin B12’s vital role in producing red blood cells and maintaining bone marrow, ensuring adequate levels from an early age is essential for proper development. The vitamin supports critical metabolic processes, making it vital during childhood growth. A varied and healthy diet is always recommended to ensure sufficient intake during this crucial developmental phase.

While vitamin B12 deficiency is more prevalent, having excessive amounts in the body is rarer but can signal underlying health issues. High vitamin B12 levels can arise from overconsumption of B12-rich foods or taking supplements without medical supervision. Symptoms of elevated B12 levels may include difficulty breathing, chest tightness, rapid heartbeats, palpitations, anxiety, insomnia, swelling, itching, or skin rashes. If these symptoms appear, consulting a doctor is essential. They might recommend reducing the intake of B12-rich foods and potentially implementing other therapies.

Tempeh, made from fermented soybeans, and kombucha are among the few plant foods containing vitamin B12, but they don’t provide enough to meet our daily requirements. Vegetarians and vegans are at a higher risk of vitamin B12 deficiency as this nutrient isn’t readily available from plant-based foods alone. Maintaining a healthy diet while following vegetarian or vegan practices necessitates consulting experienced nutritionists and taking vitamin B12 supplements. Regularly checking blood levels is also essential to ensure adequate intake, as vitamin B12 cannot be obtained in sufficient quantities from a strictly plant-based diet.

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